Selected publications

Memory development in the brain

Chai XJ, Ofen N, Gabrieli JDE, Whitfield-Gabrieli S. Development of deactivation of the default-mode network during episodic memory formation. NeuroImage 84: 932-938 (2014).

Chai XJ, Ofen N, Gabrieli JDE, Whitfield-Gabrieli S. Selective development of anticorrelated networks in the intrinsic functional organization of the human brain. Journal of Cognitive Neuroscience 26: 501-513 (2014).

Ofen N, Chai XJ, Schuil K, Whitfield-Gabrieli S, Gabrieli JDE. The development of brain systems associated with successful memory retrieval of scenes. Journal of Neuroscience 32: 10012-10020 (2012).

Chai XJ, Ofen N, Jacobs LF, Gabrieli JDE. Scene complexity: influence on perception, memory, and development in the medial temporal lobe. Frontiers in Human Neuroscience 4: 21 (2010).

Brain networks shaped by language learning experience

Kousaie S, Chai XJ, Sander K, Klein D. Simultaneous learning of two languages from birth positively impacts intrinsic functional connectivity and cognitive control. Brain and Cognition, 117: 49-56 (2017).

Barbeau EB, Chai XJ, Chen JK, Soles J, Berken J, Baum S, Watkin K, Klein D. The role of the left inferior parietal lobule in second language learning: an intensive language training fMRI study. Neuropsychologia 98:169-176 (2017)

Chai XJ, Berken J, Barbeau EB, Soles J, Callahan M, Chen JK, Klein D. Intrinsic functional connectivity in the adult brain and success in second language learning. Journal of Neuroscience 36: 755-761 (2016). [Highlighted in US News, SFN News, McGill News]

 Berken J, Chai XJ, Chen JK, Gracco V, Klein D. Effects of early and late bilingualism on resting-state functional connectivity. Journal of Neuroscience 36: 1165-1172 (2016).

Altered brain networks in atypical development and clinical populations

Chai XJ, Hirshfeld-Becker D, Doehrmann O, Leonard J, Salvatore J, Brown A, Biederman J, Whitfield-Gabrieli S, Gabrieli JDE. Altered intrinsic functional brain architecture in children at familial risk of major depression. Biological Psychiatry 80: 848-858 (2016).[Highlighted in MIT News, Smithsonian

Hung Y, Saygin Z, Biederman J, Hirshfeld-Becker D, Uchida M, Doehrmann O, Han M, Chai XJ, Kenworthy T, Yarmakd P, Gaillarde SL, Whitfield-Gabrieli S, and Gabrieli JDE. Impaired frontal-limbic white matter maturation in children at risk for major depression. Cerebral Cortex. 27:4478-4491 (2017).

 Chai XJ, Hirshfeld-Becker D, Doehrmann O, Leonard J, Salvatore J, Brown A, Biederman J, Whitfield-Gabrieli S, Gabrieli JDE. Functional and structural brain correlates of risk for major depression in children with familial depression. NeuroImage: Clinical 8: 398-407 (2015).

Whitfield-Gabrieli S, Ghosh S, Castañón AN, Saygin Z, Doehrmann O, Chai XJ, Reynolds GO, Hofmann SG, Pollack MH, Gabrieli JDE. Brain connectomics predict response to treatment in social anxiety disorder. Molecular Psychiatry 21: 680-685 (2016). [Highlighted in MIT News] 


Chai XJ, Castañón AN, Öngür D, Whitfield-Gabrieli S. Anticorrelations in resting state networks without global regression. NeuroImage 59: 1420-1428 (2012).   [Cited 408 times (Google Scholar)

Whitfield-Gabrieli S, Nieto-Castañón A, Ghosh S, Egorova N, Chai XJ, Gollub RL. Artifact detection, rejection and quality assurance of fMRI data increase accuracy in task activation and functional connectivity studies. In revision.

For a full list of publications, visit